Interstitial brachytherapy for penile carcinoma: a multicentric survey (259 patients)
Identifieur interne : 00C632 ( Main/Exploration ); précédent : 00C631; suivant : 00C633Interstitial brachytherapy for penile carcinoma: a multicentric survey (259 patients)
Auteurs : R. Rozan [France] ; E. Albuisson [France] ; B. Giraud [France] ; D. Donnarieix [France] ; M. Delannes [France] ; J. Pigneux [France] ; S. Hoffstetter [France] ; A. Gerbaulet [France] ; P. Chinet-Charrot [France] ; A. Goupil [France] ; J. E. Couette [France] ; M. H. Hay [France] ; G. Chaplain [France] ; B. Castelain [France] ; B. Hassel [France] ; P. Mere [France] ; P. Cellier [France]Source :
- Radiotherapy and Oncology [ 0167-8140 ] ; 1995.
English descriptors
- Teeft :
- Anticancer institutes, Bilateral dissection, Bilateral involvement, Brachytherapy, Brachytherapy parameters, Carcinoma, Causesof death, Centre, Circumcision, Complication, Conservative treatment, Dissection, Endpoint, Endpoint factor, Epidermoid carcinoma, Exclusive brachytherapy, External beam irradiation, First lymphatic dissection, Further study, Glans, Groin dissection, Gross tumor volume, Histological specimenswere, Implantation, Inguinal, Inguinal irradiation, Inguinal node dissection, International commission, Interstitial, Interstitial brachytherapy, Interstitial implantation, Interstitial irradiation, Iridium, Iridium wires, Jackson stage, Late side effects, Linear activity, Local control, Lymph, Lymph node dissection, Lymph node involvement, Lymphatic, Lymphatic dissection, Lymphatic inguinal node dissection, Monofactorial analysis, Nodal, Nodal invasion, Nodal positivity, Nodal treatment, Node, Oncologic mkdicale, Oncology, Other patients, Overall survival, Penectomy, Penile, Penile cancer, Penile carcinoma, Penis, Phimosis, Physical examination, Place henri dunant, Prepuce, Present study, Primary treatment, Primary tumor, Prognostic, Prognostic factors, Radiation therapy, Radiation units, Radiotherapy, Recurrence, Regional lymph nodes, Rozan, Side effects, Significant difference, Small number, Small tumors, Squamous cell carcinoma, Squamouscell carcinoma, Statistical analysis, Surgery, Surgery radiotherapy, Surgical management, Survival curves, Survival rates, Therapeutic indications, Total dose, Total penectomy, Tumor infiltration, Tumor recurrence, Tumor size, Unilateral involvement, Urethral, Urethral stenosis, Urethral stricture.
Abstract
Abstract: Although cancer of the penis is a rare disease, we have collected 506 cases through a multicentric study. In the present study we analyse the results obtained from 259 patients treated by interstitial brachytherapy from 1959 to 1989. Among the 259 patients, 184 males had exclusive brachytherapy (group A) while 75 received a combination of surgery and brachytherapy and/or external beam irradiation (EBI) (group B). Five- and 10-year survival rates are, respectively: overall survival, 66 and 52%; cause-specific survival, 88 and 88%; disease-free survival, 78 and 67%. One hundred and forty-three patients in group A (78%) and 48 (64%) in group B avoided mutilation of the penis while late side effects occurred in 137 259 patients (53%). Survival depends on the volume of the tumor and the presence of involved nodes; systematic groin dissection does not however seem advisable.
Url:
DOI: 10.1016/0167-8140(95)01574-Z
Affiliations:
- France
- Aquitaine, Auvergne (région administrative), Auvergne-Rhône-Alpes, Basse-Normandie, Bourgogne, Bourgogne-Franche-Comté, Grand Est, Haute-Normandie, Hauts-de-France, Languedoc-Roussillon, Lorraine (région), Midi-Pyrénées, Nord-Pas-de-Calais, Nouvelle-Aquitaine, Occitanie (région administrative), Pays de la Loire, Rhône-Alpes, Région Bretagne, Région Normandie
- Angers, Bordeaux, Caen, Clermont-Ferrand, Dijon, Lille, Lyon, Montpellier, Nancy, Rennes, Rouen, Toulouse, Vandœuvre-lès-Nancy
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 002802
- to stream Istex, to step Curation: 002769
- to stream Istex, to step Checkpoint: 002A47
- to stream Main, to step Merge: 00CE89
- to stream Main, to step Curation: 00C632
Le document en format XML
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Rozan</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Radiothérapie, Centre Jean Perrin, 58 Rue Montalembert, B.P. 392, 63011 Clermont-Ferrand Cedex 1</wicri:regionArea><placeName><region type="region" nuts="2">Auvergne-Rhône-Alpes</region><region type="old region" nuts="2">Auvergne (région administrative)</region><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation></author><author><name sortKey="Albuisson, E" sort="Albuisson, E" uniqKey="Albuisson E" first="E." last="Albuisson">E. 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Delannes</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Radiothérapie, Centre Claudius Regaud, Toulouse</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Midi-Pyrénées</region><settlement type="city">Toulouse</settlement></placeName></affiliation></author><author><name sortKey="Pigneux, J" sort="Pigneux, J" uniqKey="Pigneux J" first="J." last="Pigneux">J. Pigneux</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Radiothérapie, Fondation Bergonié, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Hoffstetter, S" sort="Hoffstetter, S" uniqKey="Hoffstetter S" first="S." last="Hoffstetter">S. Hoffstetter</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Radiothérapie, Centre Alexis Vautrin, Vandoeuvre les Nancy</wicri:regionArea><placeName><region type="region" nuts="2">Grand Est</region><region type="old region" nuts="2">Lorraine (région)</region><settlement type="city">Vandœuvre-lès-Nancy</settlement><settlement type="city" wicri:auto="agglo">Nancy</settlement></placeName></affiliation></author><author><name sortKey="Gerbaulet, A" sort="Gerbaulet, A" uniqKey="Gerbaulet A" first="A." last="Gerbaulet">A. Gerbaulet</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Radiothérapie, Institut Gustave Roussy, Rue Camille Desmoulins, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Chinet Charrot, P" sort="Chinet Charrot, P" uniqKey="Chinet Charrot P" first="P." last="Chinet-Charrot">P. Chinet-Charrot</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Oncologie médicale, Centre Henri Becquerel, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Goupil, A" sort="Goupil, A" uniqKey="Goupil A" first="A." last="Goupil">A. Goupil</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Oncologie médicale, Centre René Huguenin, Saint-Cloud</wicri:regionArea><wicri:noRegion>Saint-Cloud</wicri:noRegion><wicri:noRegion>Saint-Cloud</wicri:noRegion></affiliation></author><author><name sortKey="Couette, J E" sort="Couette, J E" uniqKey="Couette J" first="J. E." last="Couette">J. E. Couette</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Radiothérapie, Centre François Baclesse, Caen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Basse-Normandie</region><settlement type="city">Caen</settlement></placeName></affiliation></author><author><name sortKey="Hay, M H" sort="Hay, M H" uniqKey="Hay M" first="M. H." last="Hay">M. H. Hay</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Radiothérapie, Centre Paul Lamarque, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Chaplain, G" sort="Chaplain, G" uniqKey="Chaplain G" first="G." last="Chaplain">G. 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Hassel</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Radiothérapie, Centre Eugène Marquis, Rennes</wicri:regionArea><placeName><region type="region">Région Bretagne</region><region type="old region">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Mere, P" sort="Mere, P" uniqKey="Mere P" first="P." last="Mere">P. Mere</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Radiothérapie, Centre Léon Bérard, Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Cellier, P" sort="Cellier, P" uniqKey="Cellier P" first="P." last="Cellier">P. Cellier</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Radiothérapie, Centre Paul Papin, Angers</wicri:regionArea><placeName><region type="region">Pays de la Loire</region><region type="old region">Pays de la Loire</region><settlement type="city">Angers</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Radiotherapy and Oncology</title><title level="j" type="abbrev">RADION</title><idno type="ISSN">0167-8140</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1995">1995</date><biblScope unit="volume">36</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="83">83</biblScope><biblScope unit="page" to="93">93</biblScope></imprint><idno type="ISSN">0167-8140</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0167-8140</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Anticancer institutes</term><term>Bilateral dissection</term><term>Bilateral involvement</term><term>Brachytherapy</term><term>Brachytherapy parameters</term><term>Carcinoma</term><term>Causesof death</term><term>Centre</term><term>Circumcision</term><term>Complication</term><term>Conservative treatment</term><term>Dissection</term><term>Endpoint</term><term>Endpoint factor</term><term>Epidermoid carcinoma</term><term>Exclusive brachytherapy</term><term>External beam irradiation</term><term>First lymphatic dissection</term><term>Further study</term><term>Glans</term><term>Groin dissection</term><term>Gross tumor volume</term><term>Histological specimenswere</term><term>Implantation</term><term>Inguinal</term><term>Inguinal irradiation</term><term>Inguinal node dissection</term><term>International commission</term><term>Interstitial</term><term>Interstitial brachytherapy</term><term>Interstitial implantation</term><term>Interstitial irradiation</term><term>Iridium</term><term>Iridium wires</term><term>Jackson stage</term><term>Late side effects</term><term>Linear activity</term><term>Local control</term><term>Lymph</term><term>Lymph node dissection</term><term>Lymph node involvement</term><term>Lymphatic</term><term>Lymphatic dissection</term><term>Lymphatic inguinal node dissection</term><term>Monofactorial analysis</term><term>Nodal</term><term>Nodal invasion</term><term>Nodal positivity</term><term>Nodal treatment</term><term>Node</term><term>Oncologic mkdicale</term><term>Oncology</term><term>Other patients</term><term>Overall survival</term><term>Penectomy</term><term>Penile</term><term>Penile cancer</term><term>Penile carcinoma</term><term>Penis</term><term>Phimosis</term><term>Physical examination</term><term>Place henri dunant</term><term>Prepuce</term><term>Present study</term><term>Primary treatment</term><term>Primary tumor</term><term>Prognostic</term><term>Prognostic factors</term><term>Radiation therapy</term><term>Radiation units</term><term>Radiotherapy</term><term>Recurrence</term><term>Regional lymph nodes</term><term>Rozan</term><term>Side effects</term><term>Significant difference</term><term>Small number</term><term>Small tumors</term><term>Squamous cell carcinoma</term><term>Squamouscell carcinoma</term><term>Statistical analysis</term><term>Surgery</term><term>Surgery radiotherapy</term><term>Surgical management</term><term>Survival curves</term><term>Survival rates</term><term>Therapeutic indications</term><term>Total dose</term><term>Total penectomy</term><term>Tumor infiltration</term><term>Tumor recurrence</term><term>Tumor size</term><term>Unilateral involvement</term><term>Urethral</term><term>Urethral stenosis</term><term>Urethral stricture</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Although cancer of the penis is a rare disease, we have collected 506 cases through a multicentric study. In the present study we analyse the results obtained from 259 patients treated by interstitial brachytherapy from 1959 to 1989. Among the 259 patients, 184 males had exclusive brachytherapy (group A) while 75 received a combination of surgery and brachytherapy and/or external beam irradiation (EBI) (group B). Five- and 10-year survival rates are, respectively: overall survival, 66 and 52%; cause-specific survival, 88 and 88%; disease-free survival, 78 and 67%. One hundred and forty-three patients in group A (78%) and 48 (64%) in group B avoided mutilation of the penis while late side effects occurred in 137 259 patients (53%). Survival depends on the volume of the tumor and the presence of involved nodes; systematic groin dissection does not however seem advisable.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Aquitaine</li><li>Auvergne (région administrative)</li><li>Auvergne-Rhône-Alpes</li><li>Basse-Normandie</li><li>Bourgogne</li><li>Bourgogne-Franche-Comté</li><li>Grand Est</li><li>Haute-Normandie</li><li>Hauts-de-France</li><li>Languedoc-Roussillon</li><li>Lorraine (région)</li><li>Midi-Pyrénées</li><li>Nord-Pas-de-Calais</li><li>Nouvelle-Aquitaine</li><li>Occitanie (région administrative)</li><li>Pays de la Loire</li><li>Rhône-Alpes</li><li>Région Bretagne</li><li>Région Normandie</li></region><settlement><li>Angers</li><li>Bordeaux</li><li>Caen</li><li>Clermont-Ferrand</li><li>Dijon</li><li>Lille</li><li>Lyon</li><li>Montpellier</li><li>Nancy</li><li>Rennes</li><li>Rouen</li><li>Toulouse</li><li>Vandœuvre-lès-Nancy</li></settlement></list><tree><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Rozan, R" sort="Rozan, R" uniqKey="Rozan R" first="R." last="Rozan">R. Rozan</name></region><name sortKey="Albuisson, E" sort="Albuisson, E" uniqKey="Albuisson E" first="E." last="Albuisson">E. Albuisson</name><name sortKey="Castelain, B" sort="Castelain, B" uniqKey="Castelain B" first="B." last="Castelain">B. Castelain</name><name sortKey="Cellier, P" sort="Cellier, P" uniqKey="Cellier P" first="P." last="Cellier">P. Cellier</name><name sortKey="Chaplain, G" sort="Chaplain, G" uniqKey="Chaplain G" first="G." last="Chaplain">G. Chaplain</name><name sortKey="Chinet Charrot, P" sort="Chinet Charrot, P" uniqKey="Chinet Charrot P" first="P." last="Chinet-Charrot">P. Chinet-Charrot</name><name sortKey="Couette, J E" sort="Couette, J E" uniqKey="Couette J" first="J. E." last="Couette">J. E. Couette</name><name sortKey="Delannes, M" sort="Delannes, M" uniqKey="Delannes M" first="M." last="Delannes">M. Delannes</name><name sortKey="Donnarieix, D" sort="Donnarieix, D" uniqKey="Donnarieix D" first="D." last="Donnarieix">D. Donnarieix</name><name sortKey="Gerbaulet, A" sort="Gerbaulet, A" uniqKey="Gerbaulet A" first="A." last="Gerbaulet">A. Gerbaulet</name><name sortKey="Giraud, B" sort="Giraud, B" uniqKey="Giraud B" first="B." last="Giraud">B. Giraud</name><name sortKey="Goupil, A" sort="Goupil, A" uniqKey="Goupil A" first="A." last="Goupil">A. Goupil</name><name sortKey="Hassel, B" sort="Hassel, B" uniqKey="Hassel B" first="B." last="Hassel">B. Hassel</name><name sortKey="Hay, M H" sort="Hay, M H" uniqKey="Hay M" first="M. H." last="Hay">M. H. Hay</name><name sortKey="Hoffstetter, S" sort="Hoffstetter, S" uniqKey="Hoffstetter S" first="S." last="Hoffstetter">S. Hoffstetter</name><name sortKey="Mere, P" sort="Mere, P" uniqKey="Mere P" first="P." last="Mere">P. Mere</name><name sortKey="Pigneux, J" sort="Pigneux, J" uniqKey="Pigneux J" first="J." last="Pigneux">J. Pigneux</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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